Brazikumab

Pharmaceutical drug
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IdentifiersCAS Number
  • 1610353-18-8
ChemSpider
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UNII
  • 50EI9G8Q6U
KEGG
  • D10912
Chemical and physical dataFormulaC6410H9830N1718O2016S50Molar mass144820.16 g·mol−1

Brazikumab (INN; development code MEDI2070) is a human monoclonal antibody designed for the treatment of Crohn's disease.[1][2] that targets IL-23.[3]

This drug was developed by MedImmune.

References

  1. ^ Statement On A Nonproprietary Name Adopted By The USAN Council - Brazikumab, American Medical Association
  2. ^ World Health Organization (2016). "International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 115" (PDF). WHO Drug Information. 30 (2).
  3. ^ Hanžel J, D'Haens GR (April 2020). "Anti-interleukin-23 agents for the treatment of ulcerative colitis". Expert Opinion on Biological Therapy. 20 (4): 399–406. doi:10.1080/14712598.2020.1697227. PMID 31760827.
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Monoclonal antibodies for the immune system
Immune system
Human
Mouse
Chimeric
Humanized

Immune activation: Dostarlimab
Other: Ibalizumab

Chimeric + humanized
Interleukin
Human
Humanized
Veterinary
Inflammatory lesions
Mouse
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