Keratoderma climactericum

Medical condition

Keratoderma climactericum
Other names	Climacteric keratoderma, Haxthausen's disease,^[1]^[2] and Acquired plantar keratoderma,^[2]
Specialty	Dermatology

Keratoderma climactericum, also known as climacteric keratoderma, Haxthausen's disease, or acquired plantar keratoderma, is a skin condition characterized by hyperkeratosis of the palms and soles beginning at about the time of menopause.^[3]^: 213^[4]

Causes

Keratoderma climactericum is either inherited through an abnormal gene, or it is acquired through a change in the health or environment of the individual.^[5]

References

^ Deschamps P, Leroy D, Pedailles S, Mandard JC (1986). "Keratoderma climactericum (Haxthausen's disease): clinical signs, laboratory findings and etretinate treatment in 10 patients". Dermatologica. 172 (5): 258–62. doi:10.1159/000249351. PMID 2943612.
^ ^a ^b Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. p. 205. ISBN 978-1-4160-2999-1.
^ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
^ Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.
^ "Palmoplantar keratoderma | DermNet NZ". www.dermnetnz.org. Retrieved 2019-12-19.

Cutaneous keratosis, ulcer, atrophy, and necrobiosis

Epidermal thickening

keratoderma: Keratoderma climactericum
Paraneoplastic keratoderma
- Acrokeratosis paraneoplastica of Bazex
Aquagenic keratoderma
Drug-induced keratoderma
psoriasis
- Keratoderma blennorrhagicum

keratosis: Seborrheic keratosis
- Clonal seborrheic keratosis
- Common seborrheic keratosis
- Irritated seborrheic keratosis
- Seborrheic keratosis with squamous atypia
- Reticulated seborrheic keratosis
- Dermatosis papulosa nigra
Keratosis punctata of the palmar creases

Necrobiosis/granuloma

Necrobiotic/palisading	Granuloma annulare Perforating Generalized Subcutaneous Granuloma annulare in HIV disease Localized granuloma annulare Patch-type granuloma annulare Necrobiosis lipoidica Annular elastolytic giant-cell granuloma Granuloma multiforme Necrobiotic xanthogranuloma Palisaded neutrophilic and granulomatous dermatitis Rheumatoid nodulosis Interstitial granulomatous dermatitis/Interstitial granulomatous drug reaction
Foreign body granuloma	Beryllium granuloma Mercury granuloma Silica granuloma Silicone granuloma Zirconium granuloma Soot tattoo Tattoo Carbon stain
Other/ungrouped	eosinophilic dermatosis Granuloma faciale

Dermis/
localized CTD

Cutaneous lupus erythematosus	chronic: Discoid Panniculitis subacute: Neonatal ungrouped: Chilblain Lupus erythematosus–lichen planus overlap syndrome Tumid Verrucous Rowell's syndrome
Scleroderma/ Morphea	Localized scleroderma Localized morphea Morphea–lichen sclerosus et atrophicus overlap Generalized morphea Atrophoderma of Pasini and Pierini Pansclerotic morphea Morphea profunda Linear scleroderma
Atrophic/ atrophoderma	Lichen sclerosus Anetoderma Schweninger–Buzzi anetoderma Jadassohn–Pellizzari anetoderma Atrophoderma of Pasini and Pierini Acrodermatitis chronica atrophicans Semicircular lipoatrophy Follicular atrophoderma Linear atrophoderma of Moulin Atrophia maculosa varioliformis cutis
Perforating	Kyrle disease Reactive perforating collagenosis Elastosis perforans serpiginosa Perforating folliculitis Acquired perforating dermatosis
Skin ulcer	Pyoderma gangrenosum
Other	Calcinosis cutis Sclerodactyly Poikiloderma vasculare atrophicans Ainhum/Pseudo-ainhum