Lenampicillin

Chemical compound
  • Rx in Japan
Identifiers
  • (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
CAS Number
  • 86273-18-9
PubChem CID
  • 65646
UNII
  • 8M568DM08K
CompTox Dashboard (EPA)
  • DTXSID1057901 Edit this at Wikidata
Chemical and physical dataFormulaC21H23N3O7SMolar mass461.49 g·mol−1

Lenampicillin is an antibiotic drug of the penicillin class. It is a produg of ampicillin; after oral administration of lenampicillin, ampicillin is rapidly formed.[1]

Lenampicillin inhibits bacterial penicillin binding proteins (transpeptidase) and is effective against a wide range of bacterial infections.[2]

Lenampicillin was developed in Japan and has been marketed there.[2]

References

  1. ^ Saito A, Nakashima M (May 1986). "Pharmacokinetic study of lenampicillin (KBT-1585) in healthy volunteers". Antimicrobial Agents and Chemotherapy. 29 (5): 948–950. doi:10.1128/aac.29.5.948. PMC 284190. PMID 3729355.
  2. ^ a b "Lenampicillin". InxightDrugs. National Center for Advancing Translational Sciences.
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