RAB31

Protein-coding gene in the species Homo sapiens

RAB31

Available structures

PDB

Ortholog search: PDBe RCSB

List of PDB id codes
2FG5

Identifiers

Aliases

RAB31, Rab22B, member RAS oncogene family

External IDs

OMIM: 605694; MGI: 1914603; HomoloGene: 5001; GeneCards: RAB31; OMA:RAB31 - orthologs

Gene location (Human)

Chr.	Chromosome 18 (human)^[1]

Band	18p11.22	Start	9,708,275 bp^[1]
Band	18p11.22	End	9,862,551 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 17 (mouse)^[2]

Band	17\|17 E1.1	Start	65,958,724 bp^[2]
Band	17\|17 E1.1	End	66,079,747 bp^[2]

RNA expression pattern

Bgee

Human

Mouse (ortholog)

Top expressed in

dorsal motor nucleus of vagus nerve

trabecular bone

internal globus pallidus

periodontal fiber

inferior olivary nucleus

saphenous vein

visceral pleura

optic nerve

tendon of biceps brachii

monocyte

Top expressed in

cumulus cell

granulocyte

endothelial cell of lymphatic vessel

stroma of bone marrow

barrel cortex

substantia nigra

ankle joint

calvaria

decidua

semi-lunar valve

More reference expression data

BioGPS


More reference expression data

Gene ontology
Molecular function	nucleotide binding GDP binding GTP binding GTPase activity protein binding
Cellular component	endosome phagocytic vesicle membrane Golgi apparatus trans-Golgi network membrane membrane early endosome phagocytic vesicle cytoplasmic vesicle cytosol plasma membrane secretory granule membrane early endosome membrane phagocytic cup early phagosome membrane
Biological process	receptor internalization phagosome maturation cellular response to insulin stimulus regulated exocytosis Golgi to plasma membrane protein transport neutrophil degranulation intracellular protein transport Rab protein signal transduction positive regulation of phagocytosis, engulfment
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


11031


106572

Ensembl


ENSG00000168461


ENSMUSG00000056515

UniProt


Q13636


Q921E2

RefSeq (mRNA)


NM_006868


NM_133685

RefSeq (protein)


NP_006859


NP_598446

Location (UCSC)

Chr 18: 9.71 – 9.86 Mb

Chr 17: 65.96 – 66.08 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human

View/Edit Mouse

Ras-related protein Rab-31 is a protein that in humans is encoded by the RAB31 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000168461 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000056515 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Chen D, Guo J, Miki T, Tachibana M, Gahl WA (September 1996). "Molecular cloning of two novel rab genes from human melanocytes". Gene. 174 (1): 129–34. doi:10.1016/0378-1119(96)00509-4. PMID 8863739.
^ "Entrez Gene: RAB31 RAB31, member RAS oncogene family".

Ng EL, Wang Y, Tang BL (September 2007). "Rab22B's role in trans-Golgi network membrane dynamics". Biochemical and Biophysical Research Communications. 361 (3): 751–7. doi:10.1016/j.bbrc.2007.07.076. PMID 17678623.
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (November 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
Brandenberger R, Wei H, Zhang S, Lei S, Murage J, Fisk GJ, Li Y, Xu C, Fang R, Guegler K, Rao MS, Mandalam R, Lebkowski J, Stanton LW (June 2004). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nature Biotechnology. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197. S2CID 27764390.
Bao X, Faris AE, Jang EK, Haslam RJ (January 2002). "Molecular cloning, bacterial expression and properties of Rab31 and Rab32". European Journal of Biochemistry. 269 (1): 259–71. doi:10.1046/j.0014-2956.2001.02645.x. PMID 11784320.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (October 1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Bonaldo MF, Lennon G, Soares MB (September 1996). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Research. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
Maruyama K, Sugano S (January 1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Osaka N (August 1975). "Target size and luminance in apparent brightness of the peripheral visual field". Perceptual and Motor Skills. 41 (1): 49–50. doi:10.2466/pms.1975.41.1.49. PMID 1178432. S2CID 11871373.