Histon acetiltransferaza

Identifikatori

EC broj

2.3.1.48

CAS broj

9054-51-7

Baze podataka

IntEnz

IntEnz pregled

BRENDA

BRENDA pristup

ExPASy

NiceZyme pregled

KEGG

KEGG pristup

MetaCyc

metabolički put

PRIAM

profil

Strukture PBP

RCSB PDB PDBe PDBj PDBsum

Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Histon acetiltransferaza (EC 2.3.1.48, nukleozom-histonska acetiltransferaza, histonska acetokinaza, histonska acetilaza, histonska transacetilaza) je enzim sa sistematskim imenom acetil-KoA:histon acetiltransferaza.^[1] Ovaj enzim katalizuje sledeću hemijsku reakciju

acetil-KoA + histon

\rightleftharpoons

KoA + acetilhiston

Ova grupa enzima ima različite specifičnosti prema histonskim akceptorima.

Reference

^ Gallwitz, D. & Sures, I. (1972). „Histone acetylation. Purification and properties of three histone-specific acetyltransferases from rat thymus nuclei”. Biochim. Biophys. Acta. 263: 315—328. PMID 5031160.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

Histone+acetyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)

Enzimi

Teme

Tipovi

EC1 Oksidoreduktaze /spisak
EC2 Transferaze /spisak
EC3 Hidrolaze /spisak
EC4 Lijaze /spisak
EC5 Izomeraze /spisak
EC6 Ligaze /spisak

B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6