PYCARD |
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بنى متوفرة |
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بنك بيانات البروتين | Ortholog search: PDBe RCSB | قائمة رموز معرفات بنك بيانات البروتين | 1UCP, 2KN6, 3J63, 5H8O | | |
معرفات |
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أسماء بديلة | PYCARD, ASC, CARD5, TMS, TMS-1, TMS1, PYD and CARD domain containing |
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معرفات خارجية | الوراثة المندلية البشرية عبر الإنترنت 606838 MGI: MGI:1931465 HomoloGene: 8307 GeneCards: 29108 |
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علم الوجود الجيني |
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وظائف جزيئية | • protein homodimerization activity • interleukin-6 receptor binding • BMP receptor binding • GO:0001948، GO:0016582 ربط بروتيني • identical protein binding • enzyme binding • cysteine-type endopeptidase activity involved in apoptotic process • Pyrin domain binding • cysteine-type endopeptidase activator activity involved in apoptotic process • myosin I binding • tropomyosin binding • protease binding • transmembrane transporter binding • protein dimerization activity • cysteine-type endopeptidase activity |
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مكونات خلوية | • سيتوبلازم • NLRP3 inflammasome complex • NLRP1 inflammasome complex • AIM2 inflammasome complex • نوية • شبكة إندوبلازمية • ميتوكندريون • IkappaB kinase complex • نواة • secretory granule lumen • azurophil granule lumen • الفراغ خارج الخلية • عصارة خلوية • GO:0009327 protein-containing complex • جسم الخلية العصبية • Golgi membrane • جهاز غولجي • غشاء |
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عمليات حيوية | • positive regulation of cysteine-type endopeptidase activity • regulation of apoptotic process • intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator • regulation of intrinsic apoptotic signaling pathway • intrinsic apoptotic signaling pathway by p53 class mediator • positive regulation of adaptive immune response • GO:0051636 defense response to Gram-negative bacterium • immune system process • cellular response to tumor necrosis factor • regulation of tumor necrosis factor-mediated signaling pathway • positive regulation of DNA-binding transcription factor activity • tumor necrosis factor-mediated signaling pathway • positive regulation of JNK cascade • negative regulation of interferon-beta production • negative regulation of I-kappaB kinase/NF-kappaB signaling • myeloid dendritic cell activation • positive regulation of T cell activation • defense response to virus • cellular response to interleukin-1 • positive regulation of apoptotic process • positive regulation of tumor necrosis factor production • positive regulation of release of cytochrome c from mitochondria • negative regulation of protein serine/threonine kinase activity • positive regulation of extrinsic apoptotic signaling pathway • inflammatory response • cellular response to lipopolysaccharide • negative regulation of NF-kappaB transcription factor activity • GO:0072468 توصيل الإشارة • GO:0097285 استماتة • مناعة فطرية • neutrophil degranulation • positive regulation of NF-kappaB transcription factor activity • activation of innate immune response • myeloid dendritic cell activation involved in immune response • positive regulation of antigen processing and presentation of peptide antigen via MHC class II • activation of cysteine-type endopeptidase activity involved in apoptotic process • positive regulation of actin filament polymerization • regulation of protein stability • positive regulation of interferon-gamma production • positive regulation of interleukin-6 production • positive regulation of activated T cell proliferation • positive regulation of cysteine-type endopeptidase activity involved in apoptotic process • macropinocytosis • positive regulation of phagocytosis • positive regulation of ERK1 and ERK2 cascade • positive regulation of T cell migration • positive regulation of defense response to virus by host • intrinsic apoptotic signaling pathway in response to DNA damage • response to bacterium • regulation of autophagy • interleukin-1 beta production • GO:0043087، GO:0032313، GO:0032319، GO:0032314، GO:0043088 regulation of GTPase activity • regulation of cysteine-type endopeptidase activity involved in apoptotic process • regulation of inflammatory response • protein homooligomerization • activation of cysteine-type endopeptidase activity • negative regulation of cytokine production involved in inflammatory response • تحلل بروتيني • positive regulation of interleukin-1 beta production |
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المصادر:Amigo / QuickGO | |
نمط التعبير عن الحمض النووي الريبوزي |
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المزيد من بيانات التعبير المرجعية |
تماثلات متسلسلة |
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أنواع | الإنسان | الفأر |
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أنتريه | 29108 | 66824 |
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Ensembl | ENSG00000103490 | ENSMUSG00000030793 |
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يونيبروت | | |
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RefSeq (رنا مرسال.) | | NM_013258، NM_145182 NM_145183، NM_013258، NM_145182 |
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RefSeq (بروتين) | | NP_660183 NP_037390، NP_660183 |
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الموقع (UCSC | n/a | Chr 7: 127.59 – 127.59 Mb |
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بحث ببمد | [1] | [2] |
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ويكي بيانات |
اعرض/عدّل إنسان | اعرض/عدّل فأر |
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