Firocoxib
COX-2 selective NSAID veterinary drug
- Veterinary Use
- Veterinary Use
- US DailyMed: Firocoxib
administration
- QM01AH90 (WHO)
- 3-(Cyclopropylmethoxy)-5,5-dimethyl-4-(4-methylsulfonylphenyl)furan-2-one
- 189954-96-9
Y
- 208910
- DB09217 Y
- 181008 Y
- Y6V2W4S4WT
- D03712 Y
- CHEBI:76136
N
- ChEMBL69998 Y
- DTXSID40870188
- Interactive image
- O=C2OC(C(=C2\OCC1CC1)\c3ccc(cc3)S(=O)(=O)C)(C)C
- InChI=1S/C17H20O5S/c1-17(2)14(12-6-8-13(9-7-12)23(3,19)20)15(16(18)22-17)21-10-11-4-5-11/h6-9,11H,4-5,10H2,1-3H3Y
- Key:FULAPETWGIGNMT-UHFFFAOYSA-NY
N
Y (what is this?) (verify)Firocoxib, sold under the brand names Equioxx and Previcox among others, is a nonsteroidal anti-inflammatory drug of the COX-2 inhibitor (coxib) class, approved for use in horses (Equioxx) and for use in dogs (Previcox).[2][4][8] Firocoxib was the first COX-2 inhibitor approved by the U.S. Food and Drug Administration for horses.[9] Firocoxib is not intended or approved for use in human medicine.[2][4][5][6][10]
Firocoxib, manufactured by Merial, was approved for veterinary use in the United States for dogs in July 2004,[11] and for horses in July 2007, as an oral paste (Equioxx) and July 2016, as tablets.[12][13]
Firocoxib is also available as a generic medication for horses[13] and for dogs.[11]
References
- ^ "Product information". Health Canada. 22 October 2009. Retrieved 9 February 2024.
- ^ a b c "Equioxx- firocoxib tablet, chewable". DailyMed. 14 July 2020. Archived from the original on 3 August 2022. Retrieved 2 August 2022.
- ^ "Equioxx- firocoxib paste". DailyMed. 24 February 2022. Archived from the original on 3 August 2022. Retrieved 2 August 2022.
- ^ a b c "Previcox- firocoxib tablet, chewable". DailyMed. 23 July 2020. Archived from the original on 3 August 2022. Retrieved 2 August 2022.
- ^ a b "Equioxx EPAR". European Medicines Agency (EMA). Archived from the original on 25 April 2022. Retrieved 2 August 2022.
- ^ a b "Previcox EPAR". European Medicines Agency (EMA). Archived from the original on 31 July 2021. Retrieved 2 August 2022.
- ^ "Coxatab EPAR". European Medicines Agency (EMA). 17 June 2022. Retrieved 9 February 2024.
- ^ "New NSAID Equioxx (firocoxib) Approved by USEF". The Horse. 2 July 2007. Archived from the original on 18 May 2011. Retrieved 18 April 2008.
- ^ Equioxx Archived 21 December 2014 at the Wayback Machine, European Medicines Agency (EMA)
- ^ a b "FDA Approves the First Generic Firocoxib Tablets for Dogs". U.S. Food and Drug Administration. 7 June 2022. Archived from the original on 3 August 2022. Retrieved 2 August 2022.
- ^ "Merial launches first firocoxib for horses". DVM 360. 1 July 2007. Retrieved 3 October 2023.
- ^ a b "FDA Approves the First Generic Firocoxib Tablets for Horses". U.S. Food and Drug Administration (FDA). 1 August 2022. Archived from the original on 3 August 2022. Retrieved 2 August 2022.
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pyrazolidines
and related substances
- Ampiroxicam
- Droxicam
- Isoxicam
- Lornoxicam
- Meloxicam
- Piroxicam
- Pivoxicam
- Tenoxicam
derivatives (profens)
- Alminoprofen
- Benoxaprofen†
- Carprofen‡
- Dexibuprofen
- Dexketoprofen
- Fenbufen
- Fenoprofen
- Flunoxaprofen
- Flurbiprofen
- Ibuprofen#
- Ibuproxam
- Indoprofen†
- Ketoprofen
- Loxoprofen
- Miroprofen
- Naproxen
- Oxaprozin
- Pelubiprofen
- Piketoprofen
- Pirprofen
- Suprofen
- Tarenflurbil
- Tepoxalin‡
- Tiaprofenic acid
- Vedaprofen‡
- Zaltoprofen
- COX-inhibiting nitric oxide donator: Naproxcinod
acids (fenamates)
(coxibs)
- Apricoxib
- Celecoxib (+tramadol)
- Cimicoxib‡
- Deracoxib‡
- Etoricoxib
- Firocoxib‡
- Lumiracoxib†
- Mavacoxib‡
- Parecoxib
- Robenacoxib‡
- Rofecoxib†
- Valdecoxib†
combinations
Key: underline indicates initially developed first-in-class compound of specific group; #WHO-Essential Medicines; †withdrawn drugs; ‡veterinary use.
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