Ksantozin monofosfat

Ksantozin monofosfat
IUPAC ime
 
5'-ksantilinska kiselina
Drugi nazivi ksantinski ribotid,
XMP
Identifikacija
CAS registarski broj 523-98-8 DaY
PubChem[1][2] 122280
ChemSpider[3] 66054 DaY
KEGG[4] C00655
MeSH Xanthosine+monophosphate
ChEBI CHEBI:15652
Jmol-3D slike Slika 1
SMILES

C1=NC2=C(N1[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O)NC(=O)NC2=O

InChI

InChI=1S/C10H13N4O9P/c15-5-3(1-22-24(19,20)21)23-9(6(5)16)14-2-11-4-7(14)12-10(18)13-8(4)17/h2-3,5-6,9,15-16H,1H2,(H2,19,20,21)(H2,12,13,17,18)/t3-,5-,6-,9-/m1/s1 DaY
Kod: DCTLYFZHFGENCW-UUOKFMHZSA-N DaY

InChI=1/C10H13N4O9P/c15-5-3(1-22-24(19,20)21)23-9(6(5)16)14-2-11-4-7(14)12-10(18)13-8(4)17/h2-3,5-6,9,15-16H,1H2,(H2,19,20,21)(H2,12,13,17,18)/t3-,5-,6-,9-/m1/s1
Kod: DCTLYFZHFGENCW-UUOKFMHZBH

Svojstva
Molekulska formula C10H13N4O9P
Molarna masa 364,206 g/mol

 DaY (šta je ovo?)   (verifikuj)

Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala

Infobox references

Ksantozin monofosfat (XMP[5]) je intermedijer u purinskom metabolizmu.[6] On je ribonukleosidni monofosfat. XMP se formira iz inozin monofosfata posredstvom IMP dehidrogenaze, dok se guanozin monofosfat (GMP) formira posredstvom GMP sintaze.

Reference

  1. ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.  edit
  2. ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1. 
  3. ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.  edit
  4. ↑ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H. 
  5. ↑ Gogia, S.; Balaram, H.; Puranik, M. (May 2011). „Hypoxanthine guanine phosphoribosyltransferase distorts the purine ring of nucleotide substrates and perturbs the pKa of bound xanthosine monophosphate.”. Biochemistry 50 (19): 4184-93. DOI:10.1021/bi102039b. PMID 21486037. 
  6. ↑ McMurry 2007: str. 1007

Literatura

  • McMurry, John (2007). Organic chemistry: a biological approach. Cengage Learning. str. 1007-. ISBN 978-0-495-01525-3. Pristupljeno 26. 3. 2012. 
  • Sigel, H; Operschall, BP; Griesser, R (2009). „Xanthosine 5'-monophosphate (XMP). Acid-base and metal ion-binding properties of a chameleon-like nucleotide”. Chemical Society reviews 38 (8): 2465-94. DOI:10.1039/b902181g. PMID 19623361. 
  • Egli, M; Pallan, PS (2010). „Crystallographic studies of chemically modified nucleic acids: A backward glance”. Chemistry & Biodiversity 7 (1): 60-89. DOI:10.1002/cbdv.200900177. PMC 2905155. PMID 20087997. 

Vidi još

Spoljašnje veze

Portal Hemija
  • p
  • r
  • u
Metabolizam purina
R5P→IMP: R5P • PRPP • PRA • GAR • FGAR • FGAM • AIR • CAIR • SAICAR • AICAR • FAICAR

IMP→AMP: Adenilosukcinat

IMP→GMP: Ksantozin monofosfat
Metabolizam pirimidina

M: MET

mt, k, c/g/r/p/y/i, f/h/s/l/o/e, a/u, n, m

k, cgrp/y/i, f/h/s/l/o/e, au, n, m, epon

m (A16/C10), i (k, c/g/r/p/y/i, f/h/s/o/e, a/u, n, m)